Technology

Isolation Principles

1

EXODUS has been developed using a dual-membrane nanofiltration system that integrates periodic negative pressure oscillation (NPO) and double-coupled ultrasonic harmonic oscillations (HO).

2
3
4
5

EXODUS can rapidly remove free nucleic acid and protein impurities from the sample, resulting in the efficient purification and enrichment of exosomes. The exosomes are precisely intercepted by nanoporous membrane, allowing for a highly targeted isolation process.

EXODUS has great potential to revolutionize exosome isolation and drive new discoveries in biomedical research and translation.

a (4)

Rapid isolation

Maximum isolation speed:

200 mL/h

ax (8)

Nature Methods, 2021, 18(2):212-218.

ax (7)

Biosensors and Bioelectronics:  X 2012,10.

a (3)

High purity and high yield

Purity ~ 99 %; Yield ~ 90 %

Protein remove
rate:99%

Exosome recovery
rate:90%

ax (6)

Urine-Equal
protein-purity

Urine-Equal
Volume-yield

fb3900c6b6c615861e2a040869fb4e3
a (2)

Wide application

Other small amount sample types

19

Plasma

23

Aqueous humor

118

Saliva

22

Tears

17

Cerebrospinal fluid

24

Synovial fluid

Sample types

Sample volumes

ax (4)
a (1)

Label-free

Only need PBS buffer

TEM image of exosome

ax (3)
ax (2)
ax (1)
55
网页 5.7